Pre_GI Gene

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Host: NC_017248 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017248:721764 Brucella melitensis NI chromosome chromosome I, complete sequence

Host Lineage: Brucella melitensis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a facultative intracellular bacteria that causes abortion in wild and domestic animals, usually goats or sheep, and undulant fever in humans. Brucellosis is a major health problem in the Mediterranean region and parts of Asia, Africa, and Latin America, where it causes severe economic losses. The disease is transmitted to humans by nonpasteurized milk and milk products or by direct contact with infected animals or carcasses.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
721764722033270ETC complex I subunitQuickGO ontologyBLASTP
722521723189669hypothetical proteinBLASTP
723410724021612exonucleaseQuickGO ontologyBLASTP
724455724700246transposaseQuickGO ontologyBLASTP
725191725736546adenylate kinaseQuickGO ontologyBLASTP
7257337272681536N-acetyltransferase GCN5QuickGO ontologyBLASTP
727243728037795helix-turn-helix domain-containing proteinQuickGO ontologyBLASTP
729140729331192hypothetical proteinBLASTP
729482729757276hypothetical proteinBLASTP
7297577318712115Integrase catalytic domain proteinQuickGO ontologyBLASTP
731837732397561hypothetical proteinBLASTP
732514732813300putative cytosolic proteinQuickGO ontologyBLASTP
732967733083117GAF domain-containing proteinQuickGO ontology
733176733676501hypothetical proteinBLASTP
734213734647435hypothetical proteinBLASTP
734655734831177hypothetical proteinBLASTP
7351237364301308hypothetical proteinBLASTP
7368817382571377ApeAQuickGO ontologyBLASTP
738247739224978hypothetical proteinBLASTP
739608740120513SH3 type 3 domain-containing proteinQuickGO ontologyBLASTP
740280740495216hypothetical proteinBLASTP
7407737419271155cystathionine beta-lyaseQuickGO ontologyBLASTP
742153742920768Bacitracin transport permease protein BCRCQuickGO ontologyBLASTP
7433757444061032general L-amino acid-binding periplasmic protein AAPJ precursorQuickGO ontologyBLASTP