Pre_GI Gene

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Host: NC_017214 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017214:191791 Bifidobacterium animalis subsp. lactis BB-12 chromosome, complete

Host Lineage: Bifidobacterium animalis; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria

General Information: Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity. Most of the ~30 known species of bifidobacteria have been isolated from the mammalian GIT, and some from the vaginal and oral cavity. All are obligate anaerobes belonging to the Actinomycetales, branch of Gram-positive bacteria with high GC content that also includes Corynebacteria, Mycobacteria, and Streptomycetes. Bifidobacterium animalis and Bifidobacterium lactis were originally considered to be separate species. Recent studies evaluating the DNA relatedness and phenotypic similarities of these species has determined that they represent a single species.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1917911938692079Multidrugproteinlipid ABC transporter family ATP-binding and permease proteinQuickGO ontologyBLASTP
1938661958391974Multidrug resistance ABC transporter ATP-binding and permease proteinQuickGO ontologyBLASTP
195836196441606MarR family transcriptional regulatorQuickGO ontologyBLASTP
19650519660399hypothetical proteinBLASTP
196645197211567OxidoreductaseQuickGO ontologyBLASTP
197325197837513patch repair proteinQuickGO ontologyBLASTP
198781198978198hypothetical proteinBLASTP
198981199250270hypothetical proteinBLASTP
199383199691309hypothetical proteinBLASTP
1997502007961047hypothetical proteinBLASTP
2008002038923093ATP-dependent helicaseQuickGO ontologyBLASTP
2038442054811638hypothetical proteinBLASTP
2055002068071308hypothetical proteinBLASTP
206823207143321hypothetical proteinBLASTP
2074152090461632hypothetical proteinBLASTP
209109209591483hypothetical proteinBLASTP
209716210090375hypothetical proteinBLASTP
2106592119301272glutamate--cysteine ligaseQuickGO ontologyBLASTP
2120042167644761Activator of R-2-hydroxyglutaryl-CoA dehydrataseQuickGO ontologyBLASTP
216924217541618membrane spanning proteinQuickGO ontologyBLASTP
217538217939402membrane spanning proteinQuickGO ontologyBLASTP
217992218891900hypothetical proteinBLASTP
218888219637750Anaerobic ribonucleoside-triphosphate reductase activating proteinQuickGO ontologyBLASTP
2199792224532475Anaerobic ribonucleoside-triphosphate reductaseQuickGO ontologyBLASTP