Pre_GI Gene

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Host: NC_017208 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017208:3928161 Bacillus thuringiensis serovar chinensis CT-43 chromosome, complete

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
39281613928736576cell division protein ftsQQuickGO ontologyBLASTP
39290283929933906UDP-N-acetylenolpyruvoylglucosamine reductaseQuickGO ontologyBLASTP
393014739313161170N-acetylglucosaminyl transferaseQuickGO ontologyBLASTP
393134539324361092stage V sporulation protein EQuickGO ontologyBLASTP
393252739338791353UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetaseQuickGO ontologyBLASTP
39338803934854975phospho-N-acetylmuramoyl-pentapeptide- transferaseQuickGO ontologyBLASTP
393487739363521476UDP-N-acetylmuramoylalanyl-D-glutamate--2 6-diaminopimelate ligaseQuickGO ontologyBLASTP
393653839384541917stage V sporulation protein Dsporulation specific DD-transpeptidaseQuickGO ontologyBLASTP
393853639406352100division specific DD-transpeptidasecell division protein ftsIQuickGO ontologyBLASTP
39407083941070363cell division protein ftsLQuickGO ontologyBLASTP
39410863942018933S-adenosyl-methyltransferase MraWQuickGO ontologyBLASTP
394238939440051617hypothetical proteinBLASTP
394408539449698852-dehydropantoate 2-reductaseQuickGO ontologyBLASTP
39452653945738474hypothetical proteinBLASTP
39457733946279507prespore specific transcriptional activator rsfAQuickGO ontologyBLASTP