Pre_GI Gene

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Host: NC_017066 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017066:995629 Rickettsia typhi str. TH1527 chromosome, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
9956299971131485NADHubiquinone oxidoreductase subunit MQuickGO ontologyBLASTP
997479998066588cytochrome c biogenesis protein CcmAQuickGO ontologyBLASTP
9997231000202480NADH dehydrogenase subunit IQuickGO ontologyBLASTP
100020910012281020NADHubiquinone oxidoreductase subunit HQuickGO ontologyBLASTP
100139710034242028NADH dehydrogenase subunit GQuickGO ontologyBLASTP
10034271003783357hypothetical proteinBLASTP
100395610065922637aconitate hydrataseQuickGO ontologyBLASTP
10067511007083333F0F1 ATP synthase subunit epsilonQuickGO ontologyBLASTP
100719710086211425F0F1 ATP synthase subunit betaQuickGO ontologyBLASTP
10087241009590867F0F1 ATP synthase subunit gammaQuickGO ontologyBLASTP
100966810112061539F0F1 ATP synthase subunit alphaQuickGO ontologyBLASTP
10113431011894552F0F1 ATP synthase subunit deltaQuickGO ontologyBLASTP
101201810133971380dihydrolipoamide dehydrogenaseQuickGO ontologyBLASTP
10136481014082435hypothetical proteinBLASTP
101570410180612358penicillin-binding protein 1AQuickGO ontologyBLASTP
101806510194021338dimethylallyladenosine tRNA methylthiotransferaseQuickGO ontologyBLASTP
10201461020628483hypothetical proteinBLASTP
102062110223481728glutathione-regulated potassium-efflux systemQuickGO ontologyBLASTP
10223451022671327hypothetical proteinBLASTP