Pre_GI Gene

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Host: NC_017066 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017066:683000 Rickettsia typhi str. TH1527 chromosome, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
6830356843721338DNA repair protein RadAQuickGO ontologyBLASTP
684369684704336hypothetical proteinBLASTP
684753685463711DNA repair protein RecOQuickGO ontologyBLASTP
686015686692678hypothetical proteinBLASTP
686879687115237hypothetical proteinBLASTP
6884186909132496translation initiation factor IF-2QuickGO ontologyBLASTP
6911416926521512transcription elongation factor NusAQuickGO ontologyBLASTP
692827693312486ribosome maturation protein RimPQuickGO ontologyBLASTP
694687695442756hemolysinQuickGO ontologyBLASTP
6955956968301236tyrosyl-tRNA synthetaseQuickGO ontologyBLASTP
6994717051525682large extracellular alpha-helical proteinQuickGO ontologyBLASTP