Pre_GI Gene

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Host: NC_017066 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017066:57571 Rickettsia typhi str. TH1527 chromosome, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
57571587701200aspartate aminotransferaseQuickGO ontologyBLASTP
5888959545657hypothetical proteinBLASTP
595426093013893-deoxy-D-manno-octulosonic-acid transferaseQuickGO ontologyBLASTP
6204062969930elongation factor TsQuickGO ontologyBLASTP
631266401388830S ribosomal protein S2QuickGO ontologyBLASTP
64418657911374cysteinyl-tRNA synthetaseQuickGO ontologyBLASTP
68152726034452hypothetical proteinBLASTP
7321073512303preprotein translocase subunit SecGQuickGO ontologyBLASTP
73744750001257prolinebetaine transporter ProP1QuickGO ontologyBLASTP
7498775871885hypothetical proteinBLASTP
7601576737723OmpW family outer-membrane proteinQuickGO ontologyBLASTP
76866782631398NADp transhydrogenase subunit betaQuickGO ontologyBLASTP
7832078880561putative cytoplasmic proteinQuickGO ontologyBLASTP
79064798828197-cyano-7-deazaguanine reductaseQuickGO ontologyBLASTP
7988680599714transcriptional activator protein CzcRQuickGO ontologyBLASTP