Pre_GI Gene

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Host: NC_017062 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017062:685321 Rickettsia typhi str. B9991CWPP chromosome, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
685321686031711DNA repair protein RecOQuickGO ontologyBLASTP
686583687260678hypothetical proteinBLASTP
687447687683237hypothetical proteinBLASTP
6889866914812496translation initiation factor IF-2QuickGO ontologyBLASTP
6917096932201512transcription elongation factor NusAQuickGO ontologyBLASTP
693395693880486ribosome maturation protein RimPQuickGO ontologyBLASTP
695255696010756hemolysinQuickGO ontologyBLASTP
6961636973981236tyrosyl-tRNA synthetaseQuickGO ontologyBLASTP
7000397057205682large extracellular alpha-helical proteinQuickGO ontologyBLASTP