Pre_GI Gene

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Host: NC_017062 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017062:61500 Rickettsia typhi str. B9991CWPP chromosome, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
6200762936930elongation factor TsQuickGO ontologyBLASTP
630936398088830S ribosomal protein S2QuickGO ontologyBLASTP
64385657581374cysteinyl-tRNA synthetaseQuickGO ontologyBLASTP
68119730204902hypothetical proteinBLASTP
7362773929303preprotein translocase subunit SecGQuickGO ontologyBLASTP
74161754171257prolinebetaine transporter ProP1QuickGO ontologyBLASTP
7540476288885hypothetical proteinBLASTP
7643277154723OmpW family outer-membrane proteinQuickGO ontologyBLASTP
77283786801398NADp transhydrogenase subunit betaQuickGO ontologyBLASTP
7873779297561putative cytoplasmic proteinQuickGO ontologyBLASTP
79481802998197-cyano-7-deazaguanine reductaseQuickGO ontologyBLASTP
8030381016714transcriptional activator protein CzcRQuickGO ontologyBLASTP
8119981657459preprotein translocase subunit SecBQuickGO ontologyBLASTP
8184682412567deoxycytidine triphosphate deaminaseQuickGO ontologyBLASTP
82683840051323hypothetical proteinBLASTP