Pre_GI Gene

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Host: NC_017062 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017062:547317 Rickettsia typhi str. B9991CWPP chromosome, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
547317548159843glycosyltransferaseQuickGO ontologyBLASTP
5481925501561965DNA helicase IIQuickGO ontologyBLASTP
5512605526241365hypothetical protein
5527605537611002threonine dehydrataseQuickGO ontologyBLASTP
5538615562152355ATP-dependent protease LaQuickGO ontologyBLASTP
5568145638096996cell surface antigen Sca3QuickGO ontologyBLASTP
5645345655621029isopentenyl pyrophosphate isomeraseQuickGO ontologyBLASTP
56709356718088tRNA-SerQuickGO ontology
567399568145747UDP-N-acetylglucosamine pyrophosphorylaseQuickGO ontologyBLASTP
568145568903759hypothetical proteinBLASTP
56892256904712650S ribosomal protein L36QuickGO ontologyBLASTP
569324570112789hypothetical proteinBLASTP