Pre_GI Gene

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Host: NC_017062 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017062:508500 Rickettsia typhi str. B9991CWPP chromosome, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
5096975107131017glycosyltransferaseQuickGO ontologyBLASTP
511489512301813diaminopimelate epimeraseQuickGO ontologyBLASTP
5122765135411266tRNA-methylthiotransferase MiaB proteinQuickGO ontologyBLASTP
5136655147171053phenylalanyl-tRNA synthetase subunit alphaQuickGO ontologyBLASTP
5147145171612448phenylalanyl-tRNA synthetase subunit betaQuickGO ontologyBLASTP
5171665183111146DNA polymerase III subunit betaQuickGO ontologyBLASTP
518657519157501hypothetical proteinBLASTP
5192225217082487leucyl-tRNA synthetaseQuickGO ontologyBLASTP
521965522576612ribonuclease DQuickGO ontologyBLASTP
522714523037324septum formation initiatorQuickGO ontologyBLASTP
523034523720687phosphatidate cytidylyltransferaseQuickGO ontologyBLASTP
523680524360681undecaprenyl pyrophosphate synthetaseQuickGO ontologyBLASTP
5245115258211311osmolarity sensor protein EnvZQuickGO ontologyBLASTP
525799526467669response regulator protein OmpRQuickGO ontologyBLASTP
526596527462867branched-chain amino acid aminotransferaseQuickGO ontologyBLASTP