Pre_GI Gene

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Host: NC_017062 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017062:244330 Rickettsia typhi str. B9991CWPP chromosome, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
244330244911582ribonuclease HIIQuickGO ontologyBLASTP
2449762469641989excinuclease ABC subunit BQuickGO ontologyBLASTP
247041247355315glutaredoxin 3QuickGO ontologyBLASTP
2474502492281779ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
2504952532122718DNA gyrase subunit AQuickGO ontologyBLASTP
254486255013528peptide deformylaseQuickGO ontologyBLASTP
255010255921912methionyl-tRNA formyltransferaseQuickGO ontologyBLASTP
256142256282141hypothetical proteinBLASTP
2599342610071074ATPaseQuickGO ontologyBLASTP
2616412627681128S-adenosylmethionine--tRNA ribosyltransferase-isomeraseQuickGO ontologyBLASTP