Pre_GI Gene

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Host: NC_016945 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016945:822229 Vibrio cholerae IEC224 chromosome II, complete sequence

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: It was isolated in November of 1994 at the city of Belém/Pa from a stool sample. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
8222298236471419GntR family transcriptional regulatorQuickGO ontologyBLASTP
8237888253681581cytochrome bd-I oxidase subunit IQuickGO ontologyBLASTP
8253818265171137cytochrome d ubiquinol oxidase subunit IIQuickGO ontologyBLASTP
826465826629165hypothetical protein
827339827542204hypothetical proteinBLASTP
8277598290811323D-serine dehydrataseQuickGO ontologyBLASTP
829292830236945DNA-binding transcriptional regulator DsdCQuickGO ontologyBLASTP
8305368316121077choloylglycine hydrolaseQuickGO ontologyBLASTP
831744831881138integrase-like proteinQuickGO ontologyBLASTP
832510832890381hypothetical proteinBLASTP
832915833310396hypothetical proteinBLASTP
833508834386879hypothetical proteinBLASTP
8343998355081110hypothetical proteinBLASTP
8355598366201062hypothetical proteinBLASTP
8377178387481032L-threonine 3-dehydrogenaseQuickGO ontologyBLASTP
83875183994411942-amino-3-ketobutyrate coenzyme A ligaseQuickGO ontologyBLASTP
841143841862720LuxR family transcriptional regulatorQuickGO ontologyBLASTP
841962842900939LysR family transcriptional regulatorQuickGO ontologyBLASTP
842894843277384glyoxylase I family proteinQuickGO ontologyBLASTP
8433558447671413iron-uptake factor PiuBQuickGO ontologyBLASTP