Pre_GI Gene

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Host: NC_016944 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016944:1547176 Vibrio cholerae IEC224 chromosome I, complete sequence

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: It was isolated in November of 1994 at the city of Belém/Pa from a stool sample. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1547176156081313638RTX toxin RtxAQuickGO ontologyBLASTP
15611811561405225RstC proteinQuickGO ontologyBLASTP
15614991561873375RstB1 proteinQuickGO ontologyBLASTP
156185115629301080RstA1 proteinQuickGO ontologyBLASTP
15630561563394339transcriptional repressor RstRQuickGO ontologyBLASTP
15639961564370375cholera enterotoxin subunit BQuickGO ontologyBLASTP
15643671565143777cholera enterotoxin A subunitQuickGO ontologyBLASTP
156524215664411200zona occludens toxinQuickGO ontologyBLASTP
15664381566722285accessory enterotoxinQuickGO ontologyBLASTP
156672815679151188hypothetical proteinBLASTP
15680221568270249colonization factorQuickGO ontologyBLASTP
15682631568406144hypothetical proteinBLASTP
15684061568786381RstB2 proteinQuickGO ontologyBLASTP
156876415698431080RstA1 proteinQuickGO ontologyBLASTP
15699691570307339transcriptional repressor RstRQuickGO ontologyBLASTP
15707971571381585hypothetical proteinBLASTP
15713741571541168hypothetical proteinBLASTP
15716191572311693hypothetical proteinBLASTP
15724411572725285hypothetical proteinBLASTP
157273015742981569plasmid replication protein CriQuickGO ontologyBLASTP
15744751575026552TlcR proteinQuickGO ontologyBLASTP
15760651576232168hypothetical proteinBLASTP
15762251576392168hypothetical proteinBLASTP
15764701577162693hypothetical proteinBLASTP
15772921577576285hypothetical proteinBLASTP
157758115791491569plasmid replication protein CriQuickGO ontologyBLASTP