Pre_GI Gene

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Host: NC_016915 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016915:928000 Rickettsia rickettsii str. Hlp#2 chromosome, complete genome

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
928105928281177MFS type sugar transporterQuickGO ontologyBLASTP
928860928979120guanosine-35-bisdiphosphate 3-pyrophosphohydrolaseQuickGO ontologyBLASTP
93007493014976tRNA-ValQuickGO ontologyBLASTP
93024693052427930S ribosomal protein S20QuickGO ontologyBLASTP
93054393095341150S ribosomal protein L17QuickGO ontologyBLASTP
9309649319861023DNA-directed RNA polymerase subunit alphaQuickGO ontologyBLASTP
93200593238838430S ribosomal protein S11QuickGO ontologyBLASTP
93241393279037830S ribosomal protein S13QuickGO ontologyBLASTP
932849933487639adenylate kinaseQuickGO ontologyBLASTP
9335039348041302preprotein translocase subunit SecYQuickGO ontologyBLASTP
93480893526946250S ribosomal protein L15QuickGO ontologyBLASTP
93528393547419250S ribosomal protein L30QuickGO ontologyBLASTP
93549893602853130S ribosomal protein S5QuickGO ontologyBLASTP
93604693639334850S ribosomal protein L18QuickGO ontologyBLASTP
93640993694253450S ribosomal protein L6QuickGO ontologyBLASTP
93695193734939930S ribosomal protein S8QuickGO ontologyBLASTP
93736993767430630S ribosomal protein S14QuickGO ontologyBLASTP
93769293823154050S ribosomal protein L5QuickGO ontologyBLASTP
93823193856033050S ribosomal protein L24QuickGO ontologyBLASTP
93856193892936950S ribosomal protein L14QuickGO ontologyBLASTP
93900493923723430S ribosomal protein S17QuickGO ontologyBLASTP
93923993945421650S ribosomal protein L29QuickGO ontologyBLASTP
93944793985741150S ribosomal protein L16QuickGO ontologyBLASTP
93987294052565430S ribosomal protein S3QuickGO ontologyBLASTP
94052794088636050S ribosomal protein L22QuickGO ontologyBLASTP
94089594117327930S ribosomal protein S19QuickGO ontologyBLASTP
94119894201982250S ribosomal protein L2QuickGO ontologyBLASTP
94202094231629750S ribosomal protein L23QuickGO ontologyBLASTP
94231394293662450S ribosomal protein L4QuickGO ontologyBLASTP
94304794369464850S ribosomal protein L3QuickGO ontologyBLASTP
94369594401231830S ribosomal protein S10QuickGO ontologyBLASTP
944009944143135hypothetical proteinBLASTP
9442539454371185elongation factor TuQuickGO ontologyBLASTP
94573494581986tRNA-TyrQuickGO ontologyBLASTP
946011946733723tRNArRNA methyltransferaseQuickGO ontologyBLASTP