Pre_GI Gene

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Host: NC_016914 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016914:926500 Rickettsia rickettsii str. Hino chromosome, complete genome

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
927036927212177MFS type sugar transporterQuickGO ontologyBLASTP
927791927910120guanosine-35-bisdiphosphate 3-pyrophosphohydrolaseQuickGO ontologyBLASTP
92900592908076tRNA-ValQuickGO ontologyBLASTP
92917792945527930S ribosomal protein S20QuickGO ontologyBLASTP
92947492988441150S ribosomal protein L17QuickGO ontologyBLASTP
9298959309171023DNA-directed RNA polymerase subunit alphaQuickGO ontologyBLASTP
93093693131938430S ribosomal protein S11QuickGO ontologyBLASTP
93134493172137830S ribosomal protein S13QuickGO ontologyBLASTP
931780932418639adenylate kinaseQuickGO ontologyBLASTP
9324349337351302preprotein translocase subunit SecYQuickGO ontologyBLASTP
93373993420046250S ribosomal protein L15QuickGO ontologyBLASTP
93421493440519250S ribosomal protein L30QuickGO ontologyBLASTP
93442993495953130S ribosomal protein S5QuickGO ontologyBLASTP
93497793532434850S ribosomal protein L18QuickGO ontologyBLASTP
93534093587353450S ribosomal protein L6QuickGO ontologyBLASTP
93588293628039930S ribosomal protein S8QuickGO ontologyBLASTP
93630093660530630S ribosomal protein S14QuickGO ontologyBLASTP
93662393716254050S ribosomal protein L5QuickGO ontologyBLASTP
93716293749133050S ribosomal protein L24QuickGO ontologyBLASTP
93749293786036950S ribosomal protein L14QuickGO ontologyBLASTP
93793593816823430S ribosomal protein S17QuickGO ontologyBLASTP
93817093838521650S ribosomal protein L29QuickGO ontologyBLASTP
93837893878841150S ribosomal protein L16QuickGO ontologyBLASTP
93880393945665430S ribosomal protein S3QuickGO ontologyBLASTP
93945893981736050S ribosomal protein L22QuickGO ontologyBLASTP
93982694010427930S ribosomal protein S19QuickGO ontologyBLASTP
94012994095082250S ribosomal protein L2QuickGO ontologyBLASTP
94095194124729750S ribosomal protein L23QuickGO ontologyBLASTP
94124494186762450S ribosomal protein L4QuickGO ontologyBLASTP
94197894262564850S ribosomal protein L3QuickGO ontologyBLASTP
94262694294331830S ribosomal protein S10QuickGO ontologyBLASTP
942940943074135hypothetical proteinBLASTP
9431849443681185elongation factor TuQuickGO ontologyBLASTP
94466594475086tRNA-TyrQuickGO ontologyBLASTP
944942945664723tRNArRNA methyltransferaseQuickGO ontologyBLASTP