Pre_GI Gene

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Host: NC_016914 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016914:772025 Rickettsia rickettsii str. Hino chromosome, complete genome

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7720257733591335DNA repair protein RadAQuickGO ontologyBLASTP
773356773670315hypothetical proteinBLASTP
773792774505714DNA repair protein RecOQuickGO ontologyBLASTP
774657774806150hypothetical proteinBLASTP
775023775715693glycoprotease family proteinQuickGO ontologyBLASTP
7757727770341263hypothetical proteinBLASTP
7774017798962496translation initiation factor IF-2QuickGO ontologyBLASTP
7801357816461512transcription elongation factor NusAQuickGO ontologyBLASTP
781657782142486ribosome maturation protein RimPQuickGO ontologyBLASTP
782316782672357hypothetical proteinBLASTP
783194783592399hypothetical proteinBLASTP
783660784088429Rrf2 family proteinQuickGO ontologyBLASTP
784083784838756hemolysinQuickGO ontologyBLASTP
7849977862321236tyrosyl-tRNA synthetaseQuickGO ontologyBLASTP
786236786520285hypothetical proteinBLASTP
786525786776252hypothetical proteinBLASTP
786844787101258hypothetical proteinBLASTP
787268787480213hypothetical proteinBLASTP
788499788714216hypothetical proteinBLASTP
788920789399480hypothetical proteinBLASTP
790515790715201hypothetical proteinBLASTP
790714790926213hypothetical proteinBLASTP