Pre_GI Gene

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Host: NC_016913 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016913:232500 Rickettsia rickettsii str. Brazil chromosome, complete genome

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
232798233121324hypothetical proteinBLASTP
233108233362255hypothetical proteinBLASTP
2334592348501392fumarate hydrataseQuickGO ontologyBLASTP
234847235299453hypothetical proteinBLASTP
235410236132723tRNArRNA methyltransferaseQuickGO ontologyBLASTP
23632423640986tRNA-TyrQuickGO ontologyBLASTP
2367062378901185elongation factor TuQuickGO ontologyBLASTP
238000238134135hypothetical proteinBLASTP
23813123844831830S ribosomal protein S10QuickGO ontologyBLASTP
23844923909664850S ribosomal protein L3QuickGO ontologyBLASTP
23920723983062450S ribosomal protein L4QuickGO ontologyBLASTP
23982724012329750S ribosomal protein L23QuickGO ontologyBLASTP
24012424094582250S ribosomal protein L2QuickGO ontologyBLASTP
24097024124827930S ribosomal protein S19QuickGO ontologyBLASTP
24125724161636050S ribosomal protein L22QuickGO ontologyBLASTP
24161824227165430S ribosomal protein S3QuickGO ontologyBLASTP
24228624269641150S ribosomal protein L16QuickGO ontologyBLASTP
24268924290421650S ribosomal protein L29QuickGO ontologyBLASTP
24290624313923430S ribosomal protein S17QuickGO ontologyBLASTP
24321424358236950S ribosomal protein L14QuickGO ontologyBLASTP
24358324391233050S ribosomal protein L24QuickGO ontologyBLASTP
24391224445154050S ribosomal protein L5QuickGO ontologyBLASTP
24446924477430630S ribosomal protein S14QuickGO ontologyBLASTP
24479424519239930S ribosomal protein S8QuickGO ontologyBLASTP
24520124573453450S ribosomal protein L6QuickGO ontologyBLASTP
24575024609734850S ribosomal protein L18QuickGO ontologyBLASTP
24611524664553130S ribosomal protein S5QuickGO ontologyBLASTP
24666924686019250S ribosomal protein L30QuickGO ontologyBLASTP
24687424733546250S ribosomal protein L15QuickGO ontologyBLASTP
2473392486401302preprotein translocase subunit SecYQuickGO ontologyBLASTP
248656249294639adenylate kinaseQuickGO ontologyBLASTP
24935324973037830S ribosomal protein S13QuickGO ontologyBLASTP
24975525013838430S ribosomal protein S11QuickGO ontologyBLASTP
2501572511791023DNA-directed RNA polymerase subunit alphaQuickGO ontologyBLASTP
25119025160041150S ribosomal protein L17QuickGO ontologyBLASTP
25161925189727930S ribosomal protein S20QuickGO ontologyBLASTP
25199425206976tRNA-ValQuickGO ontologyBLASTP
253164253283120guanosine-35-bisdiphosphate 3-pyrophosphohydrolaseQuickGO ontologyBLASTP
253862254038177MFS type sugar transporterQuickGO ontologyBLASTP
255163255699537hypothetical proteinBLASTP
255671255970300hypothetical proteinBLASTP
256212256445234hypothetical proteinBLASTP