Pre_GI Gene

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Host: NC_016911 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016911:926918 Rickettsia rickettsii str. Hauke chromosome, complete genome

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
926918927094177MFS type sugar transporterQuickGO ontologyBLASTP
927673927792120guanosine-35-bisdiphosphate 3-pyrophosphohydrolaseQuickGO ontologyBLASTP
92888792896276tRNA-ValQuickGO ontologyBLASTP
92905992933727930S ribosomal protein S20QuickGO ontologyBLASTP
92935692976641150S ribosomal protein L17QuickGO ontologyBLASTP
9297779307991023DNA-directed RNA polymerase subunit alphaQuickGO ontologyBLASTP
93081893120138430S ribosomal protein S11QuickGO ontologyBLASTP
93122693160337830S ribosomal protein S13QuickGO ontologyBLASTP
931662932300639adenylate kinaseQuickGO ontologyBLASTP
9323169336171302preprotein translocase subunit SecYQuickGO ontologyBLASTP
93362193408246250S ribosomal protein L15QuickGO ontologyBLASTP
93409693428719250S ribosomal protein L30QuickGO ontologyBLASTP
93431193484153130S ribosomal protein S5QuickGO ontologyBLASTP
93485993520634850S ribosomal protein L18QuickGO ontologyBLASTP
93522293575553450S ribosomal protein L6QuickGO ontologyBLASTP
93576493616239930S ribosomal protein S8QuickGO ontologyBLASTP
93618293648730630S ribosomal protein S14QuickGO ontologyBLASTP
93650593704454050S ribosomal protein L5QuickGO ontologyBLASTP
93704493737333050S ribosomal protein L24QuickGO ontologyBLASTP
93737493774236950S ribosomal protein L14QuickGO ontologyBLASTP
93781793805023430S ribosomal protein S17QuickGO ontologyBLASTP
93805293826721650S ribosomal protein L29QuickGO ontologyBLASTP
93826093867041150S ribosomal protein L16QuickGO ontologyBLASTP
93868593933865430S ribosomal protein S3QuickGO ontologyBLASTP
93934093969936050S ribosomal protein L22QuickGO ontologyBLASTP
93970893998627930S ribosomal protein S19QuickGO ontologyBLASTP
94001194083282250S ribosomal protein L2QuickGO ontologyBLASTP
94083394112929750S ribosomal protein L23QuickGO ontologyBLASTP
94112694174962450S ribosomal protein L4QuickGO ontologyBLASTP
94186094250764850S ribosomal protein L3QuickGO ontologyBLASTP
94250894282531830S ribosomal protein S10QuickGO ontologyBLASTP
942822942956135hypothetical proteinBLASTP
9430669442501185elongation factor TuQuickGO ontologyBLASTP
94454794463286tRNA-TyrQuickGO ontologyBLASTP
944824945546723tRNArRNA methyltransferaseQuickGO ontologyBLASTP
945657946109453hypothetical proteinBLASTP
9461069474971392fumarate hydrataseQuickGO ontologyBLASTP
947594947848255hypothetical proteinBLASTP
947835948158324hypothetical proteinBLASTP
9484999498571359cell division protein FtsZQuickGO ontologyBLASTP
950359950781423hypothetical proteinBLASTP
950961951317357ecotinQuickGO ontologyBLASTP
951463952035573hypothetical proteinBLASTP
9523839536841302AmpG proteinQuickGO ontologyBLASTP
9538009550321233ATP-dependent RNA helicase RhlEQuickGO ontologyBLASTP