Pre_GI Gene

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Host: NC_016911 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016911:771916 Rickettsia rickettsii str. Hauke chromosome, complete genome

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7719167732501335DNA repair protein RadAQuickGO ontologyBLASTP
773247773561315hypothetical proteinBLASTP
773683774396714DNA repair protein RecOQuickGO ontologyBLASTP
774548774697150hypothetical proteinBLASTP
774914775606693glycoprotease family proteinQuickGO ontologyBLASTP
7756637769251263hypothetical proteinBLASTP
7772927797872496translation initiation factor IF-2QuickGO ontologyBLASTP
7800267815371512transcription elongation factor NusAQuickGO ontologyBLASTP
781548782033486ribosome maturation protein RimPQuickGO ontologyBLASTP
782207782563357hypothetical proteinBLASTP
783085783483399hypothetical proteinBLASTP
783551783979429Rrf2 family proteinQuickGO ontologyBLASTP
783974784729756hemolysinQuickGO ontologyBLASTP
7848887861231236tyrosyl-tRNA synthetaseQuickGO ontologyBLASTP
786127786369243hypothetical proteinBLASTP
786416786667252hypothetical proteinBLASTP
786735786992258hypothetical proteinBLASTP
787159787371213hypothetical proteinBLASTP
788390788605216hypothetical proteinBLASTP
788811789290480hypothetical proteinBLASTP
790406790606201hypothetical proteinBLASTP
790605790817213hypothetical proteinBLASTP