Pre_GI Gene

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Host: NC_016909 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016909:926000 Rickettsia rickettsii str. Arizona chromosome, complete genome

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
926555926731177MFS type sugar transporterQuickGO ontologyBLASTP
927310927429120guanosine-35-bisdiphosphate 3-pyrophosphohydrolaseQuickGO ontologyBLASTP
92852492859976tRNA-ValQuickGO ontologyBLASTP
92869692897427930S ribosomal protein S20QuickGO ontologyBLASTP
92899392940341150S ribosomal protein L17QuickGO ontologyBLASTP
9294149304361023DNA-directed RNA polymerase subunit alphaQuickGO ontologyBLASTP
93045593083838430S ribosomal protein S11QuickGO ontologyBLASTP
93086393124037830S ribosomal protein S13QuickGO ontologyBLASTP
931299931937639adenylate kinaseQuickGO ontologyBLASTP
9319539332541302preprotein translocase subunit SecYQuickGO ontologyBLASTP
93325893371946250S ribosomal protein L15QuickGO ontologyBLASTP
93373393392419250S ribosomal protein L30QuickGO ontologyBLASTP
93394893447853130S ribosomal protein S5QuickGO ontologyBLASTP
93449693484334850S ribosomal protein L18QuickGO ontologyBLASTP
93485993539253450S ribosomal protein L6QuickGO ontologyBLASTP
93540193579939930S ribosomal protein S8QuickGO ontologyBLASTP
93581993612430630S ribosomal protein S14QuickGO ontologyBLASTP
93614293668154050S ribosomal protein L5QuickGO ontologyBLASTP
93668193701033050S ribosomal protein L24QuickGO ontologyBLASTP
93701193737936950S ribosomal protein L14QuickGO ontologyBLASTP
93745493768723430S ribosomal protein S17QuickGO ontologyBLASTP
93768993790421650S ribosomal protein L29QuickGO ontologyBLASTP
93789793830741150S ribosomal protein L16QuickGO ontologyBLASTP
93832293897565430S ribosomal protein S3QuickGO ontologyBLASTP
93897793933636050S ribosomal protein L22QuickGO ontologyBLASTP
93934593962327930S ribosomal protein S19QuickGO ontologyBLASTP
93964894046982250S ribosomal protein L2QuickGO ontologyBLASTP
94047094076629750S ribosomal protein L23QuickGO ontologyBLASTP
94076394138662450S ribosomal protein L4QuickGO ontologyBLASTP
94149794214464850S ribosomal protein L3QuickGO ontologyBLASTP
94214594246231830S ribosomal protein S10QuickGO ontologyBLASTP
942459942593135hypothetical proteinBLASTP
9427039438871185elongation factor TuQuickGO ontologyBLASTP
94418494426986tRNA-TyrQuickGO ontologyBLASTP
944461945183723tRNArRNA methyltransferaseQuickGO ontologyBLASTP
945294945746453hypothetical proteinBLASTP
9457439471341392fumarate hydrataseQuickGO ontologyBLASTP
947231947485255hypothetical proteinBLASTP
947472947795324hypothetical proteinBLASTP
9481369494941359cell division protein FtsZQuickGO ontologyBLASTP
949996950418423hypothetical proteinBLASTP
950598950954357ecotinQuickGO ontologyBLASTP
951100951672573hypothetical proteinBLASTP
9520209530841065AmpG proteinQuickGO ontologyBLASTP
9534369546681233ATP-dependent RNA helicase RhlEQuickGO ontologyBLASTP