Pre_GI Gene

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Host: NC_016908 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016908:926446 Rickettsia rickettsii str. Colombia chromosome, complete genome

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
926446926622177MFS type sugar transporterQuickGO ontologyBLASTP
927201927320120guanosine-35-bisdiphosphate 3-pyrophosphohydrolaseQuickGO ontologyBLASTP
92841592849076tRNA-ValQuickGO ontologyBLASTP
92858792886527930S ribosomal protein S20QuickGO ontologyBLASTP
92888492929441150S ribosomal protein L17QuickGO ontologyBLASTP
9293059303271023DNA-directed RNA polymerase subunit alphaQuickGO ontologyBLASTP
93034693072938430S ribosomal protein S11QuickGO ontologyBLASTP
93075493113137830S ribosomal protein S13QuickGO ontologyBLASTP
931190931828639adenylate kinaseQuickGO ontologyBLASTP
9318449331451302preprotein translocase subunit SecYQuickGO ontologyBLASTP
93314993361046250S ribosomal protein L15QuickGO ontologyBLASTP
93362493381519250S ribosomal protein L30QuickGO ontologyBLASTP
93383993436953130S ribosomal protein S5QuickGO ontologyBLASTP
93438793473434850S ribosomal protein L18QuickGO ontologyBLASTP
93475093528353450S ribosomal protein L6QuickGO ontologyBLASTP
93529293569039930S ribosomal protein S8QuickGO ontologyBLASTP
93571093601530630S ribosomal protein S14QuickGO ontologyBLASTP
93603393657254050S ribosomal protein L5QuickGO ontologyBLASTP
93657293690133050S ribosomal protein L24QuickGO ontologyBLASTP
93690293727036950S ribosomal protein L14QuickGO ontologyBLASTP
93734593757823430S ribosomal protein S17QuickGO ontologyBLASTP
93758093779521650S ribosomal protein L29QuickGO ontologyBLASTP
93778893819841150S ribosomal protein L16QuickGO ontologyBLASTP
93821393886665430S ribosomal protein S3QuickGO ontologyBLASTP
93886893922736050S ribosomal protein L22QuickGO ontologyBLASTP
93923693951427930S ribosomal protein S19QuickGO ontologyBLASTP
93953994036082250S ribosomal protein L2QuickGO ontologyBLASTP
94036194065729750S ribosomal protein L23QuickGO ontologyBLASTP
94065494127762450S ribosomal protein L4QuickGO ontologyBLASTP
94138894203564850S ribosomal protein L3QuickGO ontologyBLASTP
94203694235331830S ribosomal protein S10QuickGO ontologyBLASTP
942350942484135hypothetical proteinBLASTP
9425949437781185elongation factor TuQuickGO ontologyBLASTP
94407594416086tRNA-TyrQuickGO ontologyBLASTP
944352945074723tRNArRNA methyltransferaseQuickGO ontologyBLASTP
945185945637453hypothetical proteinBLASTP
9456349470251392fumarate hydrataseQuickGO ontologyBLASTP
947122947376255hypothetical proteinBLASTP
947363947686324hypothetical proteinBLASTP
9480279493851359cell division protein FtsZQuickGO ontologyBLASTP
949887950309423hypothetical proteinBLASTP
950489950845357ecotinQuickGO ontologyBLASTP
950991951563573hypothetical proteinBLASTP