Pre_GI Gene

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Host: NC_016845 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016845:3024041 Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
302404130248117713-hydroxybutyrate dehydrogenaseQuickGO ontologyBLASTP
30248313025703873LysR family transcriptional regulatorQuickGO ontologyBLASTP
30258103026589780acetolactate decarboxylaseQuickGO ontologyBLASTP
302659930282781680acetolactate synthase large subunitQuickGO ontologyBLASTP
30283023029072771short chain dehydrogenaseQuickGO ontologyBLASTP
30302363030772537putative acetyl transferaseQuickGO ontologyBLASTP
303084830339643117acridine efflux pumpQuickGO ontologyBLASTP
30340023034430429hypothetical proteinBLASTP
30351163035505390putative transport proteinQuickGO ontologyBLASTP
30357883036492705response regulatorQuickGO ontologyBLASTP
303648930375501062sensor histidine protein kinase RstA regulatorQuickGO ontologyBLASTP
30375473038482936glycosyltransferaseQuickGO ontologyBLASTP
303871930397561038peptidase U61 LD-carboxypeptidase AQuickGO ontologyBLASTP
30410783041467390hypothetical proteinBLASTP
30433723043710339cytochrome c-type biogenesis protein CcmIQuickGO ontologyBLASTP
30437043044213510hypothetical proteinBLASTP
30442103044656447cytochrome c-type biogenesis protein CcmHQuickGO ontologyBLASTP
30446683045222555heme lyasedisulfide oxidoreductase thioldisulfide interchange proteinQuickGO ontologyBLASTP
304521930471711953cytochrome c-type biogenesis proteinQuickGO ontologyBLASTP
30471683047626459cytochrome c biogenesisQuickGO ontologyBLASTP
30476103047840231heme exporter protein CQuickGO ontologyBLASTP
30478373048574738heme ABC transporter membrane proteinQuickGO ontologyBLASTP
30486243049283660heme exporter permease componentQuickGO ontologyBLASTP
30492803049903624cytochrome c biogenesis protein CcmAQuickGO ontologyBLASTP
304998730513271341gluconate dehydrogenase cytochrome c subunitQuickGO ontologyBLASTP
305133830531221785gluconate 2-dehydrogenaseQuickGO ontologyBLASTP