Pre_GI Gene

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Host: NC_016838 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016838:85487 Klebsiella pneumoniae subsp. pneumoniae HS11286 plasmid pKPHS1,

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
8548786017531putative transcriptional regulatorQuickGO ontologyBLASTP
8615086329180hypothetical protein
8665187301651hypothetical protein
8735287555204hypothetical protein
8815088632483hypothetical protein
8883789034198hypothetical protein
8898789139153hypothetical protein
8924489663420hypothetical proteinBLASTP
8977190070300hypothetical protein
9021990431213hypothetical protein
9044490662219hypothetical protein
9129291414123hypothetical protein
9253992724186hypothetical proteinBLASTP
92708944051698hypothetical proteinBLASTP
94609961651557type I restriction enzymeQuickGO ontologyBLASTP
96162973581197Restriction modification system DNA specificity domain proteinQuickGO ontologyBLASTP
9743497715282HsdR proteinQuickGO ontologyBLASTP
976691001642496putative type I restriction-modification enzyme R subunitQuickGO ontologyBLASTP
100260100550291putative type I restriction-modification enzyme R subunitQuickGO ontologyBLASTP
100612100827216putative DNA modification methylaseQuickGO ontology
100956101534579hypothetical protein
101662101817156hypothetical protein
101817102188372TciAQuickGO ontologyBLASTP
102542103204663hypothetical protein
103228103896669putative ribonuclease HQuickGO ontologyBLASTP
104424104657234hypothetical protein
104860105453594hypothetical proteinBLASTP
105638106471834hypothetical protein
106597107154558hypothetical proteinBLASTP
107164107583420hypothetical protein
107647108291645hypothetical protein
108291108761471putative dihydrofolate reductaseQuickGO ontologyBLASTP