Pre_GI Gene

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Host: NC_016822 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016822:4889656 Shigella sonnei 53G, complete genome

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
48886614889659999iron-dicitrate transporter permease subunitQuickGO ontologyBLASTP
48896564890558903iron-dicitrate transporter substrate-binding subunitQuickGO ontologyBLASTP
489060348929272325outer membrane receptorQuickGO ontologyBLASTP
48930144893967954fec operon regulator FecRQuickGO ontologyBLASTP
48939644894485522RNA polymerase sigma factor FecIQuickGO ontologyBLASTP
48947774895052276IS1 repressor protein InsAQuickGO ontologyBLASTP
48949714895264294transposase ORF B IS1QuickGO ontologyBLASTP
48952654895474210insertion element proteinQuickGO ontologyBLASTP
48955684895843276IS1 repressor protein InsAQuickGO ontologyBLASTP
48957624896265504IS1 ORF2QuickGO ontologyBLASTP
48970134897270258hypothetical protein
48973914897666276IS1 repressor protein InsAQuickGO ontologyBLASTP
48975854898088504IS1 ORF2QuickGO ontologyBLASTP
48983354899315981hypothetical proteinBLASTP
489938049004861107N-acetylneuraminic acid mutarotaseQuickGO ontologyBLASTP
49005064901222717Oligogalacturonate-specific porinQuickGO ontologyBLASTP
49022064902481276IS1 repressor protein InsAQuickGO ontologyBLASTP
49024004902903504IS1 ORFQuickGO ontologyBLASTP
49028974903040144hypothetical proteinBLASTP
49036934904019327tyrosine recombinaseQuickGO ontologyBLASTP
49040304904533504IS1 ORF2QuickGO ontologyBLASTP
49044524904727276IS1 repressor protein InsAQuickGO ontologyBLASTP
49047614904949189hypothetical protein
49050004905437438outer membrane usher protein type 1 fimbrial synthesisQuickGO ontologyBLASTP
49054484905951504IS1 ORFQuickGO ontologyBLASTP
49058704906145276IS1 repressor protein InsAQuickGO ontologyBLASTP
49064944907390897outer membrane usher protein type 1 fimbrial synthesisQuickGO ontologyBLASTP
490764949088241176ISCps8 transposaseQuickGO ontologyBLASTP
49089834909753771outer membrane usher protein FimDQuickGO ontologyBLASTP
49097634910293531minor fimbrial subunitQuickGO ontologyBLASTP
49103064910809504minor component of type 1 fimbriaeQuickGO ontologyBLASTP
49108294911731903FimH mannose-binding proteinQuickGO ontologyBLASTP
491189549132381344fructuronate transporterQuickGO ontologyBLASTP