Pre_GI Gene

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Host: NC_016822 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016822:3065426 Shigella sonnei 53G, complete genome

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
30654263065641216lysis protein SQuickGO ontologyBLASTP
30668223067385564bacteriophage proteinQuickGO ontologyBLASTP
30678663068252387antitermination protein Q-like proteinQuickGO ontologyBLASTP
30682423068613372endonucleaseQuickGO ontologyBLASTP
30686133068870258bacteriophage proteinQuickGO ontologyBLASTP
306886730702581392replicative DNA helicaseQuickGO ontologyBLASTP
30703743071279906IS2 transposase TnpBQuickGO ontologyBLASTP
30712373071602366IS2 repressor TnpAQuickGO ontologyBLASTP
30716783072502825hypothetical proteinBLASTP
30727003072906207hypothetical protein
30733963073539144hypothetical proteinBLASTP
307396830754461479hypothetical proteinBLASTP
30759553076230276IS1 repressor protein InsAQuickGO ontologyBLASTP
30761493076652504IS1 ORF2QuickGO ontologyBLASTP
3076978307705376tRNA-MetQuickGO ontologyBLASTP
30771133077616504IS1 ORF2QuickGO ontologyBLASTP
30775353077810276IS1 repressor protein InsAQuickGO ontologyBLASTP
30778893078392504IS1 ORF2QuickGO ontologyBLASTP
30783113078586276IS1 repressor protein InsAQuickGO ontologyBLASTP
30801333080405273alpha amylaseQuickGO ontologyBLASTP
30807413081718978carbon starvation induced proteinQuickGO ontologyBLASTP
308173830830061269hydroxyglutarate oxidaseQuickGO ontologyBLASTP
308302930844771449succinate-semialdehyde dehydrogenase IQuickGO ontologyBLASTP
3084491308577112814-aminobutyrate aminotransferaseQuickGO ontologyBLASTP
308608230874821401gamma-aminobutyrate transporterQuickGO ontologyBLASTP
30875033088165663DNA-binding transcriptional regulator CsiRQuickGO ontologyBLASTP
30881663088615450LysM domainBON superfamily proteinQuickGO ontologyBLASTP
30886993088857159hypothetical proteinBLASTP
30890403089339300ArsR family transcriptional regulatorQuickGO ontologyBLASTP
30893493089873525hypothetical proteinBLASTP