Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:9664000 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
966401996654191401hypothetical proteinBLASTP
966541696669421527modulator of DNA gyraseQuickGO ontologyBLASTP
966756196720844524Rhs proteinQuickGO ontologyBLASTP
96720819672524444hypothetical proteinBLASTP
96726299672934306hypothetical proteinBLASTP
96731219673612492N-acetyltransferase GCN5QuickGO ontologyBLASTP
96736279673845219hypothetical proteinBLASTP
96738069674723918hypothetical proteinBLASTP
96748699675291423hypothetical proteinBLASTP
967547896761827053-oxoacyl-ACP reductaseQuickGO ontologyBLASTP
96761889676958771enoyl-acyl-carrier-protein reductaseQuickGO ontologyBLASTP
96772689677600333hypothetical protein
96776059678303699GntR family transcriptional regulatorQuickGO ontologyBLASTP
967840796797141308integral membrane transporterQuickGO ontologyBLASTP
96798379679953117hypothetical protein
96801649680373210hypothetical protein
96805079681025519hypothetical proteinBLASTP
968108696823421257putative phosphoserine phosphataseQuickGO ontologyBLASTP
968242196838811461integral membrane proteinQuickGO ontology