Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:9551123 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
95511239551986864AraC family transcription regulatorQuickGO ontologyBLASTP
95520399552911873hypothetical protein
95530489553404357hypothetical protein
95536929554420729transcription regulator ArsRQuickGO ontologyBLASTP
95544899555469981hypothetical proteinBLASTP
95555479555966420hypothetical proteinBLASTP
95561489556957810hypothetical proteinBLASTP
95569549557145192hypothetical proteinBLASTP
95572149557873660hypothetical protein
955833995619473609hypothetical proteinBLASTP
95620309562755726GntR family transcriptional regulatorQuickGO ontologyBLASTP
956286395642661404sodiumdicarboxylate symporterQuickGO ontologyBLASTP
9564275956562113473-carboxy-ciscis-muconate cycloisomeraseQuickGO ontologyBLASTP
95656909565833144hypothetical protein
95658519566261411transcriptional regulatorQuickGO ontologyBLASTP
95663629567219858hydrolaseQuickGO ontologyBLASTP
95672399568081843hypothetical proteinBLASTP
95682619568797537hypothetical proteinBLASTP
956918195717902610phosphoenolpyruvate synthaseQuickGO ontologyBLASTP
957195995741542196serinethreonine protein kinaseQuickGO ontologyBLASTP