Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:9422650 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
942265094236781029C4-dicarboxylate transportermalic acid transport proteinQuickGO ontologyBLASTP
942399394277093717nitrate reductase alpha chain NarG3QuickGO ontologyBLASTP
942771194293931683nitrate reductase beta chain NarH3QuickGO ontologyBLASTP
94293999430046648nitrate reductase delta chain NarJ3QuickGO ontologyBLASTP
94300439430804762nitrate reductase gamma chain NarI3QuickGO ontologyBLASTP
94307469431297552MarR family transcriptional regulatorQuickGO ontologyBLASTP
943164694330611416putative amino acid decarboxylaseQuickGO ontologyBLASTP
943305894345121455putative monooxygenaseQuickGO ontologyBLASTP
94345129434967456hypothetical proteinBLASTP
94350339435746714hypothetical proteinBLASTP
943590294373321431putative pyruvate kinaseQuickGO ontologyBLASTP
94373739438140768hypothetical proteinBLASTP
94384229439054633two-component system response regulatorQuickGO ontologyBLASTP
94391569439872717branched-chain amino acid ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
94398699440771903branched-chain amino acid transport system ATP-binding proteinQuickGO ontologyBLASTP
944077794425161740putative branched-chain amino acid ABC transporter permeaseQuickGO ontologyBLASTP
94425309443462933putative branched-chain amino acid ABC transporter permeaseQuickGO ontologyBLASTP
944356194447781218branched-chain amino acid transport system substrate-binding proteinQuickGO ontologyBLASTP