Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:93754 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
92753937571005allophanate hydrolase subunit 2QuickGO ontologyBLASTP
9375494491738allophanate hydrolase subunit 1QuickGO ontologyBLASTP
9451195320810lactam utilization proteinQuickGO ontologyBLASTP
95351967271377major facilitator superfamily transporterQuickGO ontologyBLASTP
9747998117639dimethylmenaquinone methyltransferaseQuickGO ontologyBLASTP
98114991901077phosphoglycerate dehydrogenaseQuickGO ontologyBLASTP
99257100210954LysR family transcriptional regulatorQuickGO ontologyBLASTP
1003971026942298oxidoreductase subunit alphaQuickGO ontologyBLASTP
102711103661951LysR family transcriptional regulatorQuickGO ontologyBLASTP
1038111075123702DNA polymerase III subunit alphaQuickGO ontologyBLASTP
107554107991438hypothetical protein
108317108802486hypothetical protein
1090711105881518putative oxygenaseQuickGO ontologyBLASTP
110670111338669G-D-S-L family lipolytic proteinQuickGO ontologyBLASTP
11149711159296hypothetical protein
111589111936348ArsR family transcriptional regulatorQuickGO ontologyBLASTP
112145112474330putative transcriptional regulatorQuickGO ontologyBLASTP
112761113186426hypothetical proteinBLASTP
1132381149711734putative sulfate transporterQuickGO ontologyBLASTP
114971115090120hypothetical protein
115309115866558hypothetical protein