Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:9076686 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
907668690790792394MMPL family proteinQuickGO ontologyBLASTP
907901290803581347hypothetical proteinBLASTP
90803779080832456hypothetical proteinBLASTP
90809399081619681two-component system regulatorQuickGO ontologyBLASTP
90819529082632681hypothetical protein
90828329083581750putative dehydrogenaseQuickGO ontologyBLASTP
908382290854441623alkaline phosphataseQuickGO ontologyBLASTP
90856579085887231hypothetical protein
90858809086767888DNA-binding proteinQuickGO ontologyBLASTP
908792690897281803radical SAM family proteinQuickGO ontologyBLASTP
90897879090410624hypothetical proteinBLASTP
909047690915821107aldoketo reductaseQuickGO ontologyBLASTP
90915799092394816endonucleaseexonucleasephosphataseQuickGO ontologyBLASTP
909318490942121029oxidoreductaseQuickGO ontologyBLASTP
909441390956061194bicyclomycin resistance proteinQuickGO ontologyBLASTP
909563690968111176beta-lactamaseQuickGO ontologyBLASTP
90968319097247417putative lyaseQuickGO ontologyBLASTP
90972589097686429putative transcriptional regulator AraC family isolated domain proteinQuickGO ontologyBLASTP
90978229098232411Glyoxalasebleomycin resistance proteindioxygenaseQuickGO ontologyBLASTP
909835091007432394uvrA-like proteinQuickGO ontologyBLASTP
910072891017501023hypothetical proteinBLASTP