Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:9050528 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
905052890518291302ATP-dependent RNA helicaseQuickGO ontologyBLASTP
90519899052240252hypothetical proteinBLASTP
90524419052593153hypothetical protein
90530939053776684hypothetical protein
905405890555481491carboxylesteraseQuickGO ontologyBLASTP
90555719056485915beta-lactamaseQuickGO ontologyBLASTP
90570639057284222hypothetical protein
905762590591931569AMP-dependent synthetase and ligaseQuickGO ontologyBLASTP
90596599059799141hypothetical protein
90610919061573483aromatic-ring-hydroxylating dioxygenase subunit betaQuickGO ontologyBLASTP
906164890626521005Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like proteinQuickGO ontologyBLASTP
90626699063460792hypothetical proteinBLASTP
90636989064261564hypothetical protein
90643739064759387hypothetical protein
90648539065206354D-cysteine desulfhydraseQuickGO ontologyBLASTP
90653669066223858hypothetical protein
906627090679071638hypothetical proteinBLASTP
906848890699811494acyl-CoA synthetaseQuickGO ontologyBLASTP
90699789070250273hypothetical protein