Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:8243727 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
824372782449861260aminotransferaseQuickGO ontologyBLASTP
824500382466791677cytochrome B subunitQuickGO ontologyBLASTP
824684082482431404putative beta-glucosidaseQuickGO ontologyBLASTP
82484128249260849cellobiose transport permeaseQuickGO ontologyBLASTP
82493578250307951cellobiose ABC transporter permease proteinQuickGO ontologyBLASTP
825039082516911302sugar binding secreted proteinQuickGO ontologyBLASTP
825203382530551023putative cellobiose transport regulatorQuickGO ontologyBLASTP
82540158254536522putative acetyltransferaseQuickGO ontologyBLASTP
82545278255252726hypothetical proteinBLASTP
82561788256870693hypothetical proteinBLASTP
825720282585001299HNH endonuclease domain proteinQuickGO ontologyBLASTP
825876882601681401cellulose 14-beta-cellobiosidaseQuickGO ontologyBLASTP
826016582612531089endo-14-beta-glucanaseQuickGO ontologyBLASTP
826166582645442880cellulose 14-beta-cellobiosidaseQuickGO ontologyBLASTP
82646148265603990glycosyl transferase family proteinQuickGO ontologyBLASTP
82656008265989390hypothetical protein
826609282685512460surface protein Sur1QuickGO ontologyBLASTP