Pre_GI Gene

Some Help

Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:8031000 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
80310828031315234phosphotransferase system IIB componentQuickGO ontologyBLASTP
80313798032110732ribonuclease PHQuickGO ontologyBLASTP
80322558032689435secreted proteinQuickGO ontologyBLASTP
80327138033315603putative deoxyribonucleotide triphosphate pyrophosphataseQuickGO ontologyBLASTP
80335048033998495hypothetical proteinBLASTP
80346298035165537hypothetical proteinBLASTP
80351778035992816hydrolaseQuickGO ontologyBLASTP
80361218036588468bacterioferritin comigratory proteinQuickGO ontologyBLASTP
80367548037074321hypothetical proteinBLASTP
80371758037516342putative 10kD chaperone subunitQuickGO ontologyBLASTP
803763080399332304penicillin-binding proteinQuickGO ontologyBLASTP
80402228041037816ABC transporter permeaseQuickGO ontologyBLASTP
80410308041911882putative integral membrane transport proteinQuickGO ontologyBLASTP
804192780430901164putative ABC transporter ATP-binding subunitQuickGO ontologyBLASTP
80431598043935777hypothetical proteinBLASTP
804397980452861308secreted proteinQuickGO ontologyBLASTP
804557280469181347hypothetical proteinBLASTP
80470258047843819putative sortaseQuickGO ontologyBLASTP
80479428048250309hypothetical protein
80483598049081723hypothetical proteinBLASTP