Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:7946000 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
79464857946778294putative DNA-binding proteinQuickGO ontologyBLASTP
79469127947877966potassium-tellurite ethidium and proflavin transporterQuickGO ontologyBLASTP
79479057948033129hypothetical protein
79480357948520486MarR family transcriptional regulatorQuickGO ontologyBLASTP
794865579500251371efflux transporterQuickGO ontologyBLASTP
79500347950681648Nitroreductase-like proteinQuickGO ontologyBLASTP
79508157951021207hypothetical protein
795107379521101038LacI family transcriptional regulatorQuickGO ontologyBLASTP
795228879535861299MalE-type ABC sugar transport system periplasmic componentQuickGO ontologyBLASTP
79536567954603948MalF-type ABC sugar transport systems permease componentQuickGO ontologyBLASTP
79547197955534816sugar ABC transporter permeaseQuickGO ontologyBLASTP
795568279573191638glycoside hydrolase family proteinQuickGO ontologyBLASTP
79573737958176804hypothetical proteinBLASTP
79583167958897582putative transcriptional regulator TetR family proteinQuickGO ontologyBLASTP
79589157959175261hypothetical protein
79594947960168675hypothetical protein
796028579624622178superfamily I DNA and RNA helicase-like proteinQuickGO ontologyBLASTP
79624947963225732hypothetical protein
79632137964013801putative deacetylaseQuickGO ontologyBLASTP
79640907964749660hypothetical proteinBLASTP
79662317966383153hypothetical protein
79666587966831174hypothetical protein