Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:7737930 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
77375717737933363hypothetical proteinBLASTP
77379307738190261hypothetical protein
77382227738650429hypothetical protein
77391337740122990ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
77401197740910792putative ABC transporter integral membrane proteinQuickGO ontologyBLASTP
774102477421541131oxidoreductaseQuickGO ontologyBLASTP
774251077440001491putative integrin-like proteinQuickGO ontologyBLASTP
77442247744520297hypothetical proteinBLASTP
77447167745438723hypothetical proteinBLASTP
77454807745701222hypothetical protein
77460207746274255hypothetical proteinBLASTP
77464377747264828putative integral membrane transport proteinQuickGO ontologyBLASTP
77473337748286954putative integral membrane transport proteinQuickGO ontologyBLASTP
774835177497091359putative substrate-binding transport lipoproteinQuickGO ontologyBLASTP
774970677518982193putative beta-galactosidaseQuickGO ontologyBLASTP
775199577530261032HTH-type transcriptional repressor PurRQuickGO ontologyBLASTP
77533987754129732hypothetical proteinBLASTP
775421577555911377putative transcriptional regulator GntR family proteinQuickGO ontologyBLASTP
775562677568821257class V aminotransferaseQuickGO ontologyBLASTP
775688277581861305major facilitator superfamily transporterQuickGO ontologyBLASTP
7758348775842376tRNA-ArgQuickGO ontology
77585677759439873phytanoyl-CoA dioxygenaseQuickGO ontologyBLASTP
77595247760090567hypothetical proteinBLASTP
77601037760942840argininosuccinate synthaseQuickGO ontologyBLASTP
77609737761164192hypothetical protein
776132177625861266hypothetical proteinBLASTP
776258677643761791non-ribosomal peptide synthetaseQuickGO ontologyBLASTP
776443277657901359hypothetical protein
77657837766391609putative thioesteraseQuickGO ontologyBLASTP
77667487767650903malonyl CoA-acyl carrier protein transacylaseQuickGO ontologyBLASTP
776770777687411035non-ribosomal peptide synthaseQuickGO ontologyBLASTP
776873877759137176amino acid adenylationQuickGO ontologyBLASTP
777605177795423492non-ribosomal peptide synthetaseQuickGO ontologyBLASTP
777953977821482610KR domain-containing proteinQuickGO ontologyBLASTP
778214577835541410non-ribosomal peptide synthetaseQuickGO ontologyBLASTP
778304377848721830multifunctional peptide synthetaseQuickGO ontologyBLASTP
77848587785061204hypothetical protein