Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:7699420 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
76994207700028609TetR family transcriptional regulatorQuickGO ontologyBLASTP
770012877011149873-oxoacyl-acyl carrier protein synthase 3QuickGO ontologyBLASTP
77013827702113732hypothetical proteinBLASTP
77022467703118873putative AraC family transcriptional regulatorQuickGO ontologyBLASTP
77034487703852405hypothetical protein
770387677049851110hypothetical protein
77050117705520510hypothetical protein
77058627706503642hypothetical proteinBLASTP
77066467707239594TetR family transcriptional regulatorQuickGO ontologyBLASTP
77073787707833456hypothetical proteinBLASTP
77079657708951987AraC family transcriptional regulatorQuickGO ontologyBLASTP
77091027709896795hypothetical proteinBLASTP
77100757710512438integral membrane proteinQuickGO ontology
77107957711241447hypothetical proteinBLASTP
77112967711619324hypothetical proteinBLASTP
77116167712077462hypothetical proteinBLASTP
77120817712584504WD-40 repeat-containing proteinQuickGO ontologyBLASTP
771253377150822550putative WD-40 repeat proteinQuickGO ontologyBLASTP
77154377715865429hypothetical proteinBLASTP
77162077717028822hypothetical proteinBLASTP
77172727717478207hypothetical proteinBLASTP
771746677202102745hypothetical proteinBLASTP