Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:7033000 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
703322270352732052magnesium or manganese-dependent protein phosphataseQuickGO ontologyBLASTP
703545970367661308hypothetical proteinBLASTP
70369157037463549MarR family transcriptional regulatorQuickGO ontologyBLASTP
70376207037898279hypothetical protein
70384067039053648ornithine cyclodeaminaseQuickGO ontologyBLASTP
703967470409091236response regulator receiverQuickGO ontologyBLASTP
704090670431462241histidine kinaseQuickGO ontologyBLASTP
704356970455631995DNA-cytosine methyltransferaseQuickGO ontologyBLASTP
70454757045972498DNA mismatch endonuclease vsrQuickGO ontologyBLASTP
70460297046217189hypothetical protein
704625870482672010abortive phage infection proteinQuickGO ontologyBLASTP
704826070492701011hypothetical proteinBLASTP
704926770520382772Putative endonuclease Z1 domain proteinQuickGO ontologyBLASTP
705210870535831476ATPaseQuickGO ontologyBLASTP
70543087055024717hypothetical proteinBLASTP
705528870580082721endonucleaseQuickGO ontologyBLASTP
705799270599471956hypothetical proteinBLASTP
70599497060587639putative mobilisation proteinQuickGO ontologyBLASTP
706062070619511332membrane proteinQuickGO ontologyBLASTP
70620367062554519IstB domain-containing protein ATP-binding proteinQuickGO ontologyBLASTP
70627317062934204hypothetical proteinBLASTP
70630887063651564hypothetical proteinBLASTP
70641357064416282hypothetical proteinBLASTP
706490070664351536LacI family transcriptional regulatorQuickGO ontologyBLASTP
706659670693132718hypothetical proteinBLASTP
70694827070324843hypothetical proteinBLASTP
707025470713361083hypothetical proteinBLASTP