Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:6999074 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
69990747000012939NmrA family proteinQuickGO ontologyBLASTP
70001227000724603TetR family transcriptional regulatorQuickGO ontologyBLASTP
70007527001243492hypothetical proteinBLASTP
70013767001564189hypothetical protein
70016737002401729putative phosphataseQuickGO ontologyBLASTP
70030897003508420hypothetical proteinBLASTP
70035227003878357Glyoxalasebleomycin resistance proteindioxygenaseQuickGO ontologyBLASTP
70041187004807690AraC family transcriptional regulatorQuickGO ontologyBLASTP
70048047004989186hypothetical proteinBLASTP
700507370068901818putative DNA-binding proteinQuickGO ontologyBLASTP
700689170083061416hypothetical proteinBLASTP
70083677009044678hypothetical proteinBLASTP
70098617010058198hypothetical proteinBLASTP
70102677010497231hypothetical protein
70111667011363198hypothetical proteinBLASTP
70113637012175813DNA-binding proteinQuickGO ontologyBLASTP
70124087013058651hypothetical proteinBLASTP
70130877013824738HNH endonucleaseQuickGO ontologyBLASTP
701397970151391161DNA-cytosine methyltransferaseQuickGO ontologyBLASTP
70150747015526453hypothetical proteinBLASTP
70155557016547993type II restriction enzymeQuickGO ontologyBLASTP
701763470191001467integral membrane proteinQuickGO ontologyBLASTP
70191757020047873tRNA-guanine-N7-methyltransferaseQuickGO ontologyBLASTP
702020670214111206hydroxyglutarate oxidaseQuickGO ontologyBLASTP
702172270231551434sporulation associated proteinQuickGO ontologyBLASTP
702414070262482109hypothetical proteinBLASTP
702640070305004101AfsR-like regulatory proteinQuickGO ontologyBLASTP