Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:6811273 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
681127368122329602-hydroxyacid dehydrogenaseQuickGO ontologyBLASTP
68122986812540243hypothetical protein
68125426813321780hypothetical protein
681331468147561443hypothetical proteinBLASTP
68147536815676924lantibiotic transport ATP-binding proteinQuickGO ontologyBLASTP
681599268171731182histidine kinaseQuickGO ontologyBLASTP
68171706817877708two component LuxR family transcriptional regulatorQuickGO ontologyBLASTP
68178816818102222hypothetical protein
68187296818899171hypothetical protein
68189006819301402hypothetical protein
681945768204851029protein-L-isoaspartate-O-methyltransferaseQuickGO ontologyBLASTP
682092868222501323hypothetical proteinBLASTP
68222656822630366hypothetical proteinBLASTP
68227956823310516hypothetical proteinBLASTP
68235226824001480hypothetical protein
682405268254851434hypothetical proteinBLASTP
68255946826280687two component LuxR family transcriptional regulatorQuickGO ontologyBLASTP
682627768277011425putative two-component system sensor kinaseQuickGO ontologyBLASTP
68278786828579702ABC transporterQuickGO ontologyBLASTP
682857668309992424hypothetical protein
683111568322661152putative serinethreonine protein kinaseQuickGO ontologyBLASTP
68324576832606150hypothetical protein
68327156832987273twin arginine translocase protein AQuickGO ontology
68329716833831861hypothetical protein
68339296834504576tellurium resistance proteinQuickGO ontologyBLASTP