Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:6509792 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
65097926510034243hypothetical protein
65100946510822729ABC transporter permeaseQuickGO ontology
65108496511775927putative ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
65117726512680909integral membrane proteinQuickGO ontologyBLASTP
651266165137791119putative ABC transporter ATP-binding subunitQuickGO ontologyBLASTP
65145196514848330hypothetical proteinBLASTP
65148356515356522hypothetical proteinBLASTP
651535665198344479Rhs proteinQuickGO ontologyBLASTP
65207966521152357hypothetical protein
65214846521756273hypothetical protein
65219296522063135hypothetical protein
65220606522458399hypothetical proteinBLASTP
65226836523435753hypothetical proteinBLASTP
65234196523631213regulatory proteinQuickGO ontologyBLASTP
65236746524264591hypothetical proteinBLASTP
65242706525181912heat shock protein HtpXQuickGO ontologyBLASTP
65253556526248894hypothetical proteinBLASTP
65263266527210885putative hydrolaseQuickGO ontologyBLASTP
65273206528132813hypothetical protein
65281296528374246hypothetical protein
652838465319863603putative ABC transporter ATP-binding proteinpermeaseQuickGO ontologyBLASTP
653200965330221014cytochrome bd-I oxidase subunit IIQuickGO ontologyBLASTP
653304565346461602putative cytochrome oxidase subunit IQuickGO ontologyBLASTP