Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:6448430 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
644843064501571728putative two component system sensor kinaseQuickGO ontologyBLASTP
64502756451012738two-component system response regulatorQuickGO ontologyBLASTP
64512596452137879hypothetical proteinBLASTP
64525926453236645hypothetical proteinBLASTP
64534866454214729hypothetical proteinBLASTP
64542996455267969oxidoreductaseQuickGO ontologyBLASTP
64554156456038624putative transcriptional regulatorQuickGO ontologyBLASTP
64561246456765642putative isochorismataseQuickGO ontologyBLASTP
64567096457035327methyltransferase family proteinQuickGO ontology
64572966457865570hypothetical protein
64579286458428501hypothetical protein
64586506458988339secreted proteinQuickGO ontologyBLASTP
645931764603931077NHL repeat-containing proteinQuickGO ontologyBLASTP
64605776460909333Lsr2-like proteinQuickGO ontologyBLASTP
64611636461591429hypothetical proteinBLASTP
64624686462863396hypothetical proteinBLASTP
64650396465161123integraseQuickGO ontology
64659176466369453hypothetical protein
646659564711334539bifunctional two-component system sensor kinaseresponse regulatorQuickGO ontologyBLASTP
64712696471865597tetR family regulatory proteinQuickGO ontologyBLASTP
647198964733051317integral membrane proteinQuickGO ontologyBLASTP
647345264751041653long-chain-fatty-acid--CoA ligaseQuickGO ontologyBLASTP