Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:5987039 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
598703959894052367Tetratricopeptide TPR_4QuickGO ontology
598959859909531356secreted proteinQuickGO ontologyBLASTP
599138059928341455regulatory proteinQuickGO ontology
59931205993869750two component LuxR family transcriptional regulatorQuickGO ontologyBLASTP
599387859950801203putative two-component system sensor kinaseQuickGO ontologyBLASTP
59950905995587498hypothetical protein
59969995997286288hypothetical protein
59974695998329861hypothetical proteinBLASTP
599834159995281188amidaseQuickGO ontologyBLASTP
59995395999958420hypothetical proteinBLASTP
600003860017711734Type IV secretory pathway VirD4 protein-like proteinQuickGO ontologyBLASTP
600176860030841317hypothetical proteinBLASTP
600332160048531533putative integral membrane proteinQuickGO ontologyBLASTP
600485860062461389hypothetical proteinBLASTP
60066416007141501hypothetical protein
60074356007764330hypothetical protein
60094866010121636secreted peptidaseQuickGO ontologyBLASTP
60103666010773408hypothetical protein