Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:5227461 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
522746152284681008putative transporter substrate-binding proteinQuickGO ontologyBLASTP
52284615229384924oligopeptide ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
522938852309981611putative transporter peptide-binding proteinQuickGO ontologyBLASTP
52312485231745498hypothetical proteinBLASTP
523176652327791014alcohol dehydrogenaseQuickGO ontologyBLASTP
52329005233739840XRE family transcriptional regulatorQuickGO ontologyBLASTP
52343715234604234hypothetical protein
52346185234815198hypothetical proteinBLASTP
5235214523530996hypothetical protein
52353725235734363hypothetical proteinBLASTP
52357315235922192hypothetical protein
523607652372211146putative peptide ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
523721452382721059putative peptide ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
52382845239243960putative peptide ABC transporter permeaseQuickGO ontologyBLASTP
52392365240165930putative peptide ABC transporter permeaseQuickGO ontologyBLASTP
524025152418821632putative peptide ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
524236452442291866putative GTP-binding elongation factorQuickGO ontologyBLASTP
52443765245011636hypothetical protein
524511752471712055putative lipoproteinQuickGO ontologyBLASTP
52474965247780285hypothetical proteinBLASTP
52479915248836846integral membrane proteinQuickGO ontologyBLASTP
524885452508181965succinate dehydrogenase flavoprotein subunitQuickGO ontologyBLASTP
52508155251585771fumarate reductase iron-sulfur subunitQuickGO ontologyBLASTP