Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:4983222 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
498322249870823861ATPGTP-binding proteinQuickGO ontologyBLASTP
49872044987317114hypothetical protein
498734049885031164serine protease membrane proteinQuickGO ontologyBLASTP
49885004989213714hypothetical protein
49896104990140531hypothetical proteinBLASTP
49904644990679216hypothetical proteinBLASTP
499076949919081140protein-L-isoaspartate-O-methyltransferaseQuickGO ontologyBLASTP
49921504992296147hypothetical protein
499254549936061062hypothetical proteinBLASTP
49938674994010144hypothetical protein
499410349962472145ATPGTP-binding proteinQuickGO ontologyBLASTP
49963754996707333integrase family proteinQuickGO ontologyBLASTP
49967384997625888short-chain dehydrogenasereductase SDRQuickGO ontologyBLASTP
49977314998288558TetR family transcriptional regulatorQuickGO ontologyBLASTP
49990774999640564hypothetical proteinBLASTP
49997965000206411hypothetical proteinBLASTP
50003065001022717hypothetical proteinBLASTP
50011345001976843hypothetical proteinBLASTP
50020415002415375hypothetical proteinBLASTP
50024125003218807NAD-dependent epimerasedehydrataseQuickGO ontologyBLASTP
50032625003729468hypothetical protein