Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:4934854 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
493485449372052352putative membrane transport proteinQuickGO ontologyBLASTP
49373144937586273hypothetical protein
49378164938577762thioesteraseQuickGO ontologyBLASTP
493865749398711215integral membrane transport proteinQuickGO ontologyBLASTP
49399894940501513acetyltransferaseQuickGO ontologyBLASTP
49405694941468900putative transcriptional regulator MerR family proteinQuickGO ontologyBLASTP
49415114942146636hypothetical protein
49421434942694552putative RNA polymerase sigma factorQuickGO ontologyBLASTP
49427264943142417hypothetical protein
49432944944112819putative transcriptional regulator XRE family proteinQuickGO ontologyBLASTP
49441024944302201hypothetical proteinBLASTP
49443144945195882hypothetical proteinBLASTP
494542749468541428HNH endonuclease domain proteinQuickGO ontologyBLASTP
49469544947661708hypothetical protein
494765149499512301NB-ARC domain-containing proteinQuickGO ontologyBLASTP
49500604950695636hypothetical proteinBLASTP
49506884950957270hypothetical proteinBLASTP
49510654952039975putative hydrolaseQuickGO ontologyBLASTP
49521014952640540hypothetical proteinBLASTP
49527724953287516MarR family transcriptional regulatorQuickGO ontology
495333749544461110hypothetical proteinBLASTP
49546984955627930hypothetical proteinBLASTP
49556584956545888putative tetR family transcriptional regulatorQuickGO ontologyBLASTP
49566284956870243hypothetical protein
495707949584821404NLPP60 family secreted proteinQuickGO ontologyBLASTP