Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:4874500 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
48748774875791915homoserine kinaseQuickGO ontologyBLASTP
487615148772661116threonine synthaseQuickGO ontologyBLASTP
487731348786051293homoserine dehydrogenaseQuickGO ontologyBLASTP
487872948801201392diaminopimelate decarboxylaseQuickGO ontologyBLASTP
48801404881138999arginyl-tRNA synthetaseQuickGO ontologyBLASTP
48814794881898420two-component system response regulatorQuickGO ontologyBLASTP
4882178488224972tRNA-ArgQuickGO ontology
488256548839111347hypothetical proteinBLASTP
488522648869201695hypothetical proteinBLASTP
488711548892352121N-6 DNA methylaseQuickGO ontologyBLASTP
488931448914102097N-6 DNA methylaseQuickGO ontologyBLASTP
489140748926301224restriction modification system DNA specificity subunitQuickGO ontologyBLASTP
489266548938791215SMC domain-containing proteinQuickGO ontologyBLASTP
48938764894490615hypothetical proteinBLASTP
489449748976973201hypothetical proteinBLASTP
48977464898159414hypothetical proteinBLASTP
48985904899270681DNA-binding proteinQuickGO ontologyBLASTP
48992804899471192hypothetical protein
489954749011631617serinethreonine protein kinaseQuickGO ontologyBLASTP
490119149032962106hypothetical proteinBLASTP
490332349043631041hypothetical protein
49049064905184279hypothetical protein
490558049067161137hypothetical proteinBLASTP
49068004907654855NERD domain-containing proteinQuickGO ontologyBLASTP