Pre_GI Gene

Some Help

Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:4073850 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
407228940738631575AMP-dependent synthetase and ligaseQuickGO ontologyBLASTP
407385040753791530AMP-dependent synthetase and ligaseQuickGO ontologyBLASTP
40753544076274921hypothetical protein
407627140772841014glycosyl transferase family proteinQuickGO ontologyBLASTP
407729540787701476hypothetical protein
40788064079054249hypothetical protein
407905440805321479putative acyl-CoA synthetaseQuickGO ontologyBLASTP
40808264081779954ABC transporter permeaseQuickGO ontologyBLASTP
408185640828871032ABC transporter permeaseQuickGO ontologyBLASTP
408294540843781434ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
40847254085252528hypothetical protein
408553940893633825putative ATPGTP-binding proteinQuickGO ontologyBLASTP
40894254089751327hypothetical proteinBLASTP
40901974090385189hypothetical protein
40904374090763327DNA-binding proteinQuickGO ontologyBLASTP
40908214091033213hypothetical proteinBLASTP
40920804092700621hypothetical protein
409294940976494701RHSYD repeat-containing proteinQuickGO ontologyBLASTP
40976494098239591hypothetical proteinBLASTP