Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:389729 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
3897293909611233ferredoxin reductaseQuickGO ontologyBLASTP
3910443927681725succinate dehydrogenase flavoprotein subunitQuickGO ontologyBLASTP
392942393676735hypothetical proteinBLASTP
3935853948501266putative transmembrane efflux proteinQuickGO ontologyBLASTP
394892395635744hypothetical proteinBLASTP
395669396634966dioxygenaseQuickGO ontologyBLASTP
396785397258474hypothetical proteinBLASTP
3973833990561674cytochrome B subunitQuickGO ontologyBLASTP
399175399405231transcription factor WhiBQuickGO ontologyBLASTP
399584400495912RNA polymerase sigma factorQuickGO ontologyBLASTP
400537401454918RNA polymerase sigma factorQuickGO ontologyBLASTP
401838402176339hypothetical proteinBLASTP
402315402503189hypothetical protein
4027944040261233major facilitator superfamily proteinQuickGO ontologyBLASTP
404107404571465hypothetical proteinBLASTP
4046814060301350dehydrogenaseQuickGO ontologyBLASTP
406114406767654hypothetical proteinBLASTP
406923407381459secreted proteinQuickGO ontologyBLASTP
407535408038504hypothetical protein
408355409278924ECF subfamily RNA polymerase sigma factorQuickGO ontologyBLASTP