Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:3763476 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
37634763764261786AraC family transcription regulatorQuickGO ontologyBLASTP
376431737655701254putative fosmidmycin resistance proteinQuickGO ontologyBLASTP
37655833766185603NADPH-dependent FMN reductaseQuickGO ontologyBLASTP
37663923767237846hypothetical proteinBLASTP
37673623768234873hypothetical proteinBLASTP
37683623769348987DeoR family transcriptional regulatorQuickGO ontologyBLASTP
376974837712771530transmembrane efflux proteinQuickGO ontologyBLASTP
37718033772297495hypothetical protein
37724473772656210hypothetical proteinBLASTP
37726663773532867putative DNA-binding proteinQuickGO ontologyBLASTP
37737453774215471regulatory proteinQuickGO ontologyBLASTP
37741973774433237hypothetical protein
37746623775261600hypothetical protein
37753083776039732aminoglycoside phosphotransferaseQuickGO ontologyBLASTP
37762973777244948dehydrogenaseQuickGO ontologyBLASTP
37773223777555234hypothetical protein
37778033778309507hypothetical protein
377838637794411056lipoate-protein ligaseQuickGO ontologyBLASTP
37795093780243735hypothetical protein
378033137818931563allantoin permeaseQuickGO ontologyBLASTP