Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:2009588 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
20095882010418831poly aspartic acid hydrolaseQuickGO ontology
201054720116291083ArsR family transcriptional regulatorQuickGO ontologyBLASTP
201180320128161014hypothetical proteinBLASTP
20128132013397585hypothetical proteinBLASTP
201339920149011503hypothetical proteinBLASTP
201502220160351014histidine ammonia-lyaseQuickGO ontologyBLASTP
20160722016449378hypothetical protein
20171922017539348hypothetical proteinBLASTP
20177762018300525transposase IS116IS110IS902QuickGO ontologyBLASTP
20190902019503414integrase catalytic regionQuickGO ontologyBLASTP
20195142019969456hypothetical protein
20202802020954675glycine-rich secreted proteinQuickGO ontology
20210852021471387hypothetical protein
202172020231951476integrin-like proteinQuickGO ontologyBLASTP
20239342024560627hypothetical proteinBLASTP
20245572024838282hypothetical protein
20251212025414294hypothetical proteinBLASTP
20256512026139489hypothetical proteinBLASTP
20263832026487105hypothetical protein
20266212026893273hypothetical protein
20269542027085132hypothetical protein
20272452027832588hypothetical proteinBLASTP
20278472028215369hypothetical protein
20286682029633966hypothetical protein
203050020320411542putative acyltransferaseQuickGO ontologyBLASTP
20320412032631591hypothetical proteinBLASTP